Patrick Viatour

Headshot of Patrick Viatour

Resident Faculty

Associate Professor

Dr. Viatour is interested in the mechanisms that govern cell division during episodes of rapid cellular proliferation. In particular, his laboratory develops a unifying theory regarding the role of the transcription factor E2f in pathological contexts such as cancer and inflammatory reactions. His long-term goal is to identify novel therapeutic strategies to harness proliferation and limit the accumulation of pathological cell populations, such as tumorigenic and pro-inflammatory cells.

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About

  • 2021–present: Associate Professor, Lankenau Institute for Medical Research
  • 2012–2021: Assistant Professor and Principal Investigator, University of Pennsylvania and Children’s Hospital of Philadelphia

Publications

  • Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies. Windmueller R, Leach JP, … Viatour P, et al. Cell Rep. 2020 Mar 3;30(9):3105-3116.e4.
  • Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCs. Mastio J, Condamine T, … Viatour P, et al. J Exp Med. 2019 Sep 2;216(9):2150-2169.
  • Promotion of growth factor signaling as a critical function of β-catenin during HCC progression. Kim E, … Viatour P. Nat Commun. 2019 Apr 23;10(1):1909.
  • Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expression. Kim E, Cheng Y, … Viatour P. J Exp Med. 2017 Jul 3;214(7):1901-1912.
  • Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression. Tarangelo A, Lo N, … Viatour P. Nat Commun. 2015 Dec 7;6:10028. doi: 10.1038/ncomms10028.
  • Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. Garfin PM, Min D, … Viatour P. J Exp Med. 2013 Jun 3;210(6):1087-97.

Education and training

Education

  • Postdoctoral Fellowship, Evolution/Cancer Biology
    Stanford University School of Medicine
  • PhD, Pharmaceutical Sciences
    University of Liege, Belgium
  • MS, Pharmaceutical Sciences
    University of Liege, Belgium
  • PharmD
    University of Liege, Belgium

Academic titles

  • 2021–present: Associate Professor, Lankenau Institute for Medical Research
  • 2012–2021: Assistant Professor and Principal Investigator, University of Pennsylvania and Children’s Hospital of Philadelphia